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Mutations
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Slide 1

Mutations

Mutations

Slide 2

Definition

Definition

A mutation is a change in an organisms DNA

Silent mutations are changes that do not result in a change to the organisms phenotype

Mutations that occur in germ cells (sperm, eggs) are passed on to offspring

Mutations in somatic (body) cells may be harmless, or may result in disease such as cancer

Slide 3

Chromosomal Mutations

Chromosomal Mutations

Slide 4

A Point Mutation Resulting in Nonsense

A Point Mutation Resulting in Nonsense

Slide 5

A Point Mutation: An Analogy

A Point Mutation: An Analogy

t h e r e d d o g b i t t h e t a n c a t

t h e r e d m o g b i t t h e t a n c a t

This point mutation changes the meaning,

resulting in nonsense

Slide 6

A Point Mutation Resulting in Missense

A Point Mutation Resulting in Missense

Slide 7

A Point Mutation: An Analogy

A Point Mutation: An Analogy

t h e r e d d o g b i t t h e t a n c a t

t h e r e d h o g b i t t h e t a n c a t

This point mutation changes the meaning,

resulting in missense

Slide 8

An Insertion Mutation in a Gene

An Insertion Mutation in a Gene

Slide 9

An Insertion Mutation: An Analogy

An Insertion Mutation: An Analogy

t h e r e d d o g b i t t h e t a n c a t

t h e r e d r d o g b i t t h e t a n c a

This insertion mutation changes the reading

frame

Slide 10

A Deletion Mutation in a Gene

A Deletion Mutation in a Gene

Slide 11

An Deletion Mutation: An Analogy

An Deletion Mutation: An Analogy

t h e r e d d o g b i t t h e t a n c a t

t h e r e d o g b i t t h e t a n c a t _

This deletion mutation changes the reading

frame

Slide 12

A Frameshift Mutation

A Frameshift Mutation

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